Fluorescent Immunoassays for Detection and Quantification of Cardiac Troponin I: A Short Review

Cardiovascular diseases are considered one of the major causes human death globally. Myocardial infarction (MI), characterized by a diminished flow blood to heart, presents highest rate morbidity and mortality among all other cardiovascular diseases. These fatal effects have triggered need for early diagnosis appropriate biomarkers so that countermeasures can be taken. Cardiac troponin, central key element muscle regulation contraction, is most specific biomarker cardiac injury “gold standard”. Due its high specificity, measurement troponin levels has become predominant indicator MI. Various forms diagnostic methods been developed far, including chemiluminescence, fluorescence immunoassay, enzyme-linked immunosorbent assay, surface plasmon resonance, electrical detection, colorimetric protein assays. However, fluorescence-based immunoassays fast, accurate sensitive in determination troponins post-MI. This review represents strategies, detection involved reported I.